english.prescrire.org > Prescrire International > N°155 - December 2014

n°155

December 2014

Issue Contents
Editorial

Free  Reporting adverse effects is essential

p.284

Marketing Authorisations


Linaclotide

p.285-288
A bacterial enterotoxin derivative with a laxative action, nothing more

Inflation of endpoints

p.286

Glycopyrronium + indacaterol

p.288
A fixed-dose combination with no advantage in COPD

Free  Trastuzumab emtansine

p.289
An inadequately assessed combination of two cytotoxic drugs

Adverse Effects


Drug-induced hearing loss

p.290-294
Many risk factors

Benzodiazepines and related drugs: pneumonia

p.294-295
Consistent data

Ivabradine and patients with coronary artery disease: more cardiovascular events

p.295
Confirmation of Prescrire's assessment

Reviews


Antibiotic therapy for acute uncomplicated pyelonephritis in women

p.296-300
Take resistance into account

Acute pyelonephritis in brief

p.297

Antibiotic resistance in Escherichia coli in France

p.298

Prescrire’s Advice

p.299
Choosing an empirical antibiotic treatment for a woman with acute uncomplicated pyelonephritis

Emergency contraception in overweight women: an IUD is preferable

p.300-301
Efficacy of levonorgestrel and ulipristal uncertain in overweight women

Outlook


European pharmacovigilance: increasingly outsourced to drug companies

p.302-307

Safety referral procedures clarified

p.304-305

Masthead


Free  Masthead

p.282

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