english.prescrire.org > Prescrire International > N°90 - August 2007

n°90

August 2007

Issue Contents
Marketing Authorisations

Palifermin (oral mucositis) (new drug)

p.135-138
Inappropriate evaluation

Sunitinib (gastrointestinal stromal tumours and metastatic renal carcinoma) (new drug)

p.138-141
For some gastrointestinal stromal tumours

Sorafenib (second-line treatment of kidney cancer) (new drug)

p.141-143
A last resort

Pioglitazone + metformin (type 2 diabetes) (new drugs)

p.144
Combination products to avoid

Rosiglitazone + glimepiride (type 2 diabetes) (new drugs)

p.144
Combination products to avoid

Pioglitazone + glimepiride (type 2 diabetes) (new drugs)

p.145
Combination products to avoid

Editor's opinion

p.145
Avoid prescribing glitazones to diabetes patients, either alone or in combination

Free  Clopidogrel (myocardial infarction) (new indication)

p.146

Editor's opinion

p.146
What a shame!

Finasteride (benign prostatic hypertrophy) (new indication)

p.147
Sexual disorders

Lopinavir + ritonavir tablets (new formulation)

p.148
A formulation suited to hot climates

A formulation suited to hot climates

p.148

Nasal azelastine for self-medication

p.149
Modest symptomatic relief from rhinitis

Adverse Effects


Free  Preventing the preventable

p.134
The methotrexate lesson

Oral methotrexate: preventing avoidable overdose

p.150-152

Editor's opinion

p.152
Prescrire's proposals: preventing oral methotrexate overdose

Leukaemia due to mitoxantrone

p.153-156

Angiotensin-II receptor antagonist + diuretic + NSAID = danger

p.156

Epoetin: dose-dependent excess mortality

p.156

Reviews


Chronic hepatitis B

p.157-162
A wider range of therapeutic options

Free  Editor's opinion

p.160
Prescrire's proposals: management of chronic hepatitis B

Obesity: weight loss without drugs

p.162-167
A balanced diet avoiding high-calorie foods, plus exercise

Many low-calorie diets

p.164

Help take calorie density into account

p.165

Encourage exercice

p.166

Juvenile idiopathic arthritis: some progress but still many uncertainties

p.168

Outlook


Free  Duplicate publications of the same trial

p.169

Free  About Prescrire Association Mieux Prescrire (AMP)

p.170-171
Professional movement aimed at promoting quality healthcare

Free  French Health Agency guidelines

p.172
Separating the good from the bad

Drug treatment for type 2 diabetes:

p.173
French Health Agency

Free  Shaping diseases: marketing departments flex their wings

p.174
Refuse commercially-motivated disease definitions

Prescrire puts patients' needs first

p.176

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