english.prescrire.org > Prescrire International > N°136 - March 2013

n°136

March 2013

Issue Contents
Editorial

Free  Going against the flow

p.60
Mediocrity prevails in the pharmaceutical industry, with a few exceptions

New Products


Topiramate + phentermine (New Drug)

p.61-64
An excessively dangerous appetite-suppressant combination

Topiramate and phentermine: a long story

p.62

Bevacizumab and advanced-stage ovarian cancer (New Indication)

p.64-67
Yet another oncological indication, but still best to avoid using this drug

Eculizumab (New Indication)

p.68
A less burdensome treatment for atypical haemolytic uraemic syndrome?

Insulin glargine in children aged 2 to 5 years (New Indication)

p.69
More practical in some cases

INN common stem: -micin

p.69

Adverse Effects


Agomelatine: a review of adverse effects

p.70-71
Market withdrawal is needed

Free  Vasoconstrictive decongestants: the authorities' dithering leaves patients in danger

p.72
The French drug regulatory agency fails to act

Free  Vasoconstrictive drugs: poisoning in children

p.72
FDA review

Medication errors made by patients

p.73
Explanations about treatments are helpful

Corticosteroids: severe psychiatric disorders

p.73
Suicide, confusion

Etifoxine: too many serious adverse effects

p.73
And no evidence of efficacy

Cimicifuga: liver transplantation

p.73
British warning

Reviews


Second-line treatment of metastatic prostate cancer

p.74-78
Prednisone and radiotherapy for symptom relief

Prescrire's advice

p.77
Metastatic prostate cancer progressing despite androgen suppression: two main options

Outlook


Free  2012 Prescrire Awards

p.79-82

Free  2012 Prescrire Drug Awards

p.80

Free  2012 Prescrire Information Awards

p.81

Free  2012 Prescrire Packaging Awards

p.82

Free  Reporting adverse effects: a practice to be encouraged

p.83
One GP's experience

Masthead


Free  Masthead

p.58

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