english.prescrire.org > Prescrire International > N°271 - June 2025

n°271

June 2025

Issue Contents
Editorial

Free  Management of conflicts of interest at the EMA: chronic failure

p.143

Marketing Authorisations


Melatonin (Adaflex°, Voquily°) in insomnia in children with ADHD

p.145-147

Melatonin (Adaflex°, Melatonin Noxarem°) in jet lag

p.147-148

Pembrolizumab (Keytruda°) in inoperable or metastatic gastric or gastro-oesophageal junction adenocarcinoma

p.149-150

Andexanet alfa (Ondexxya°) in xaban-associated bleeding

p.151

Luspatercept (Reblozyl°) in anaemia associated with "non-transfusion-dependent" beta-thalassaemia

p.152-153

Aflibercept (Eylea°) in retinopathy of prematurity

p.153-154

Empagliflozin (Jardiance°) in type 2 diabetes from 10 years of age

p.155

Riociguat (Adempas°) in pulmonary arterial hypertension in children weighing 50 kg and over

p.155

Tirzepatide in heart failure in adults with obesity

p.156-157

Ataluren (Translarna°): conditional marketing authorisation finally revoked by the European Commission

p.157

Adverse Effects


GLP-1 agonists: depression, suicidal thoughts or behaviour (continued)

p.158-161

Calcium supplementation: cardiovascular risks (continued)

p.162-163

Overprescription of PPIs: increased mortality and morbidity

p.164

Benzoyl peroxide: formation of benzene following exposure to heat

p.164

Valaciclovir: more cases of acute kidney injury with neurotoxicity

p.165

Common stem: -gliflozin

p.165

Outlook


Free  The finances of Association Mieux Prescrire: 2024 annual report

p.166

Free  Update to the Declaration of Helsinki

p.167

Free  A "prescription" from French civil society for a new pharmaceutical policy

p.167

Free  French Senate resolution on the European "pharmaceutical package"

p.167

Masthead


Free  Masthead

p.142

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