english.prescrire.org > Prescrire International > N°257 - March 2024

n°257

March 2024

Issue Contents
Editorial

Free  40 years without sales representatives

p.59

Marketing Authorisations


Voxelotor (Oxbryta°) in sickle-cell disease

p.61-63

Tildrakizumab (Ilumetri°) in plaque psoriasis: 200 mg in a pre-filled syringe and 100 mg in a pre-filled pen

p.64

Amivantamab (Rybrevant°) in non-small cell lung cancer with an EGFR exon 20 insertion mutation

p.65

Osimertinib (Tagrisso°) as adjuvant treatment in certain lung cancers

p.66

Trastuzumab deruxtecan (Enhertu°) in HER2-positive gastric cancers after failure of chemotherapy combined with trastuzumab

p.67-68

Intranasal fentanyl (Instanyl° DoseGuard°): finally made safer

p.68-69

Editors' opinion. Don't procrastinate when it comes to safety

p.69

Crizanlizumab (Adakveo°): revocation of a marketing authorisation granted too hastily

p.70

Vosoritide (Voxzogo°): syringe graduated in international units of insulin!

p.71

Adverse Effects


Pregabalin and gabapentin: sometimes fatal overdoses

p.72-74

Inset. Pregabalin: avoid its use for focal seizures and generalised anxiety disorder, just as for neuropathic pain

p.73

Crizotinib and sofosbuvir + velpatasvir: increased risk of heart failure and bradycardia

p.74

Levonorgestrel-releasing IUDs: increased frequency of ectopic pregnancy

p.75

Common stem: -prost-

p.75

Outlook


The French National Authority for Health's cost-effectiveness evaluations

p.76-81

Medical devices mimicking medicinal products: the European Court of Justice confirms a strict stance

p.81-83

Mediator°: delays in the reporting of adverse effects

p.83

Masthead


Free  Masthead

p.58

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