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Spotlight

Every month, the subjects in Prescrire’s Spotlight.

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Covid-19 : Follow Prescrire's independent, evidence-based analysis of the pandemic

 COVID-19  Prescrire's editors are publishing an ongoing series of articles featuring independent analysis of developments related to the covid-19 pandemic. Useful and practical information, to help healthcare professionals gain a clear and balanced view.
1 July 2021

Low-dose methotrexate: 2-year follow-up of adverse events

FEATURED REVIEW Low-dose methotrexate is a useful first-line treatment in a range of autoimmune diseases such as rheumatoid arthritis. A 2-year follow-up of several thousand patients provides new estimates of the frequency of adverse events.
Full review (2 pages) available for download by subscribers.
1 July 2021

In the July issue of Prescrire International: fusidic acid + betamethasone valerate cream (Dermafusone°) and infected atopic eczema

FREE DOWNLOAD Atopic eczema is sometimes complicated by infection, most often caused by Staphylococcus aureus ("golden staph"), with the development of pustules and crusting. How do Prescrire's editors rate fusidic acid + betamethasone valerate cream in this situation?
Full text available for free download.
1 July 2021

Show your face!

 Editorial  Are there any amphetamine derivatives still on the market? Yes, and healthcare professionals would do well to be able to spot them in order to anticipate their effects, in particular their adverse effects, and especially their cardiovascular adverse effects.
1 July 2021

Human papillomavirus vaccine (Gardasil 9°): useful in young men too

The 9-valent human papillomavirus vaccine (Gardasil 9°) probably has a positive harm-benefit balance in the men who are  the most at risk of developing papillomavirus-related cancer.
1 July 2021

Proton pump inhibitors: avoid unjustified risks, and know how to "deprescribe"

It is better to be aware of the harms of prolonged use of proton pump inhibitors (drugs for gastrointestinal disorders), and to avoid prescribing or advising these drugs too readily.
1 July 2021

Food supplements: too readily authorised and sometimes dangerous

Several factors contribute to a major ongoing confusion between food supplements and medicinal products. Large numbers of safety signals increasingly indicate the need for caution, whereas the benefit of taking food supplements remains uncertain.
1 July 2021

Oral semaglutide (Rybelsus°): more uncertainty than with subcutaneous liraglutide

FEATURED REVIEW Semaglutide was first authorised in the European Union as a solution for weekly subcutaneous injections. It was authorised more recently in oral tablet form. How do Prescrire's editors rate this new product?
Full review (3 pages) available for download by subscribers.
1 June 2021

In the June issue of Prescrire International: Non-metastatic, castration-resistant prostate cancer

FREE DOWNLOAD Survival extended with the addition of apalutamide or enzalutamide.
Full text available for free download.
1 June 2021

Covid-19 drugs and vaccines: big money and winning alliances

 Editorial   The market for covid-19 drugs and vaccines is huge, involving billions of patients, with tens of billions of dollars potentially up for grabs. Business as usual? Not quite.
1 June 2021

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