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Spotlight

Every month, the subjects in Prescrire’s Spotlight.

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Dolutegravir + rilpivirine (Juluca°) dual therapy in HIV infection

FEATURED REVIEW First-line therapy for patients with HIV infection is usually based on triple therapy. When sustained virological suppression has been achieved, treatment "simplification" can sometimes be considered. Is the two-drug regimen dolutegravir + rilpivirine (Juluca°) any better than other treatment options?
Full review (3 pages) available for download by subscribers.
1 November 2019

In the November issue of Prescrire International - Gliptins: joint pain and exposure to NSAIDs

FREE DOWNLOAD In the Adverse Effects section of the November issue, the results of a study by the independent French medical journal Prescrire, based on data from France's national health insurance system.
Full text available for free download.
1 November 2019

Gemtuzumab ozogamicin (Mylotarg°) in acute myeloid leukaemia: no proven benefits

According to currently available clinical evaluation data, gemtuzumab ozogamicin (Mylotarg°) does not provide tangible benefits for patients with acute myeloid leukaemia.
1 November 2019

Fenspiride (Pneumorel°): serious adverse effects reported over two decades

Despite serious adverse effects reported for more than 20 years, fenspiride (Pneumorel°) was only withdrawn from the market in 2019.
1 November 2019

Industrial protectionism and medicines: too many damaging effects

Pharmaceutical companies benefit from strong industrial protection which allows them to charge exorbitant prices for their medicines for a very long time.
1 November 2019

New special section: "Mediator° - the criminal trial"

09 October 2019

  The 2019 "Prescrire Prize" is awarded in Paris to
  3 noteworthy books about health and healthcare

The recipients of the 2019 "Prescrire Prize" book awards were announced on 3 October 2019. The prize is awarded to works of particular interest to the general public and/or healthcare professionals.
03 October 2019

Axicabtagene ciloleucel (Yescarta°) in certain types of lymphoma when other treatment options have been exhausted

FEATURED REVIEW Axicabtagene ciloleucel  is a CAR (chimeric antigen receptor) T-cell therapy. It increases the chances of survival in certain situations but frequently provokes serious adverse effects. There is a pressing need for more thorough clinical evaluation.
Full review (3 pages) available for download by subscribers.
1 October 2019

In the October issue of Prescrire International: clear shortcomings in the independence of French medical schools

FREE DOWNLOADInvestigation by a nonprofit organisation revealed poor application of a charter signed by deans of French medical and dental schools.
Full text available for free download.
1 October 2019

"Faces of Mediator", a new book published by Prescrire

Les Visages du Mediator It was after seeing the French film "La Fille de Brest", an adaptation of the book by pulmonologist and whistle-blower Irène Frachon, that the photographer Marc Dantan first got the idea of taking portraits of the victims of Mediator° (benfluorex), in the hope that "bringing faces into the light could perhaps raise awareness of the silent suffering". That was the beginning of this book, which presents in 208 pages some 180 photographs, along with a foreword by Irène Frachon, a summary of the history of the Mediator° disaster, and an afterword by Prescrire. Texts in French and English.
1 October 2019

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