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Spotlight

Every month, the subjects in Prescrire’s Spotlight.

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Antibiotics: repeated treatments before the age of two could be a factor in obesity

Antibiotics disrupt the intestinal flora (intestinal microbiota) and could be a factor in weight gain. Prescription of antibiotics for children should not be automatic but should be evaluated on a case-by-case basis.
1 June 2018

Independence, in the service of patients' best interests

Prescrire is 100% financed by its subscribers, which guarantees its freedom from the influence of any special interests – be they industrial or institutional. This is the precondition for reliable, unbiased information and continuing education for healthcare professionals.
1 June 2018

Wholly self-financed through subscriptions, Prescrire makes its accounts public every year

1 June 2018

Metopimazine: cardiac disorders

FEATURED REVIEW Metopimazine has received much less attention than domperidone in regard to its cardiovascular adverse effects, but the limited data available suggest that it probably exposes patients to a risk similar to that of domperidone.
Full review (4 pages) available for download by subscribers.
1 May 2018

In the May issue of Prescrire International: Psychiatric disorders following in utero exposure to diethylstilbestrol (DES)

FREE DOWNLOAD In utero exposure to DES results in a variety of harmful effects, including long-term harms. Psychiatric disorders reported for "DES daughters" and "DES sons" include depression, bipolar disorder, behavioural disorders and schizophrenia.
Full text available for free download.
1 May 2018

Exploratory trials, surrogate endpoints: not a robust basis for marketing authorisation

To serve the best interests of patients, it is more necessary than ever to base marketing authorisation decisions on robust data.
1 May 2018

New cancer drugs: poorly evaluated, ineffective and overpriced

Many new cancer drugs are sold by drug companies at exorbitant prices, while their therapeutic benefit – when there is one – is usually modest.
1 May 2018

Warts: beware of acid-based wart removers

In recent years, in France and elsewhere, deep burns and necrosis, sometimes with permanent after-effects, have been reported with concentrated acid-based topical wart removers.
1 May 2018

"Preventing Overdiagnosis 2018": an international conference in Copenhagen, 20-22 August 2018

The not-for-profit group "Preventing Overdiagnosis", dedicated to "winding back the harms of too much medicine", has announced plans for its 2018 conference.
1 May 2018

Treating intermittent claudication: first encourage patients to follow a walking exercise programme

FEATURED REVIEW Some patients with lower limb peripheral artery disease experience pain while walking, due to a reduced ability to increase arterial circulation. What is the harm-benefit balance of treatments aimed at improving their walking capacity?
Full review (5 pages) available for download by subscribers.
1 April 2018

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