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Spotlight

Every month, the subjects in Prescrire’s Spotlight.

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Independent French journal Prescrire publishes its annual update of drugs to avoid, in the name of better patient care

Médicaments à écarter - bilan 2018In conjunction with the annual Prescrire Drug, Packaging and Information Awards, the nonprofit French medical journal Prescrire has published its annual review identifying drugs that are clearly more harmful than beneficial.
25 January 2018

Ataluren (Translarna°) and Duchenne muscular dystrophy. No proof of efficacy and poorly documented harms

FEATURED REVIEW Duchenne muscular dystrophy is a fatal, severely disabling disease that profoundly affects the lives of patients and their carers. But even in this very serious situation, there is no justification for proposing a drug with no proven efficacy beyond a placebo effect, and with poorly documented adverse effects.
Full review (4 pages) available for download by subscribers.
1 January 2018

In the January issue of Prescrire International: Primary prevention of cardiovascular disease

FREE DOWNLOAD This month's sample page from the Reviews section makes the point that statins and hypotensive drugs ought not necessarily to be prescribed for everyone who may be at risk.
Full text available for free download.
1 January 2018

Drugs to treat rare diseases: abuses spell risks for patients

Poorly evaluated drugs and exorbitant prices, a growing risk for patients.
1 January 2018

Drug-induced vocal cord damage

Some drugs induce vocal cord damage.
1 January 2018

Medicines: better to evaluate them prior to commercialisation

Drugs are less and less meticulously evaluated before they are commercialised. But post-marketing evaluations are not thorough enough, and this puts patients at risk.
1 January 2018

Making rational choices about drug treatment while breast-feeding

FEATURED REVIEW What are the principles for choosing whether and how to treat a nursing woman, without denying her access to useful drugs or harming her breastfed child?
Full review (5 pages) available for download by subscribers.
1 December 2017

In the December issue of Prescrire International: valproic acid and pregnancy

FREE DOWNLOAD A recently released study estimates that several thousand children in France who were exposed in utero to valproic acid or one of its derivatives between 1967 and 2016 were affected by at least one major congenital malformation.
Full text available for free download.
1 December 2017

Moderate nociceptive pain in adults: first-choice drugs

In patients with moderate nociceptive pain, the first-choice analgesic is paracetamol or, if unsuitable, a NSAID (ibuprofen or naproxen), or else morphine at the lowest effective dose, if necessary.
1 December 2017

Induction of labour: information and consent still inadequate

In France, a survey revealed that women are given insufficient information prior to induction of labour, and their consent is often not sought.
1 December 2017

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