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Spotlight

Every month, the subjects in Prescrire’s Spotlight.

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Medical cannabis: an experimental programme in France in 2021

The medical use of Cannabis sativa L., also known as hemp or cannabis, appears to be an option in the treatment of certain types of pain, despite its limited evaluation.
1 May 2021

Baclofen: at moderate doses, an option for some alcohol-dependent patients

In addition to medical support, baclofen, at moderate doses of around 30 mg per day, is an option of limited usefulness.
1 May 2021

Beware of "spin" in clinical trials

"Spin doctors" are not doctors in the medical sense, but rather public relations specialists whose job it is to enhance the image of an entity or individual. "Spin" however, in the sense of massaged facts, exists in medicine, where it obstructs the reliable evaluation of new drugs.
1 May 2021

Larotrectinib (Vitrakvi°) and cancers with an NTRK gene fusion. Grossly inadequate evaluation as of early 2021

FEATURED REVIEW Larotrectinib (Vitrakvi°) is the first drug to have been authorised in the European Union for adults and children with a tumour that harbours an NTRK gene fusion. Is this "targeted therapy" on target? What does its authorisation tell us about the evaluation process?
Full review (5 pages) available for download by subscribers.
1 April 2021

In the April issue of Prescrire International - Hydrochlorothiazide in hypertension: an acceptable first choice

FREE DOWNLOAD In countries where it is available, chlorthalidone is the first-choice thiazide diuretic. In France, where there is no available medicinal product containing chlorthalidone alone, the first-line thiazide diuretic is hydrochlorothiazide. How do these two drugs compare?
Full text available for free download.
1 April 2021

40 years: life goes on, so does Prescrire

 Editorial  The women and men who "make" and "are" Prescrire share strong values and work together to support a unique multidisciplinary movement for quality healthcare, launched 40 years ago.
1 April 2021

Drugs in 2020: a brief review

Just nine of the 109 new drugs, combinations, drug strengths, pharmaceutical forms or indictions analysed and rated in our French edition in 2020 constituted a notable therapeutic advance.
1 April 2021

Valproic acid: probable endocrine disruptor

Some of the adverse effects of valproic acid are linked to disruption of the human body's hormone systems. Children, especially those exposed in utero, and adolescents are particularly sensitive to effects of this type.
1 April 2021

Nasal decongestants withdrawn from the pan-European market

1 April 2021

• Safety signals: loss of sense of smell = danger

As the unending wave of medical information hits a fever pitch, it's more important then ever to remember to follow one's nose.
1 April 2021

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