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Spotlight

Every month, the subjects in Prescrire’s Spotlight.

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Venetoclax (Venclyxto°): another drug made available on the market too soon

Ventoclax inhibits a protein often present in abnormal lymphocytes in cases of chronic lymphocytic leukaemia. But does venetoclax extend the patient’s life span? We don’t know because we don’t have a comparative trial.
1 November 2018

  The 2018 "Prescrire Prize" is awarded in Paris to
  4 noteworthy books about health and healthcare

The recipients of the 2018 "Prescrire Prize" book awards were announced on 4 October 2018. The prize is awarded to works of particular interest to the general public and/or healthcare professionals.
04 October 2018

Bezlotoxumab (Zinplava°) and recurrence of C. difficile infection: No proven effect against serious complications, and cardiotoxicity

FEATURED REVIEW Given the serious complications associated with Clostridium difficile infection, treatment that safely reduces the risk of recurrences in high-risk patients would constitute a therapeutic advance. Bezlotoxumab's ability to deliver this advance has not been demonstrated. Full review (2 pages) available for download by subscribers.
1 October 2018

In the October issue of Prescrire International - Dexrazoxane in children: European disagreements and arbitration

FREE DOWNLOAD In 2017, dexrazoxane was re-approved in the European Union for use in children treated with high doses of anthracyclines. However, uncertainties remain.
Full text available for free download.
1 October 2018

Pregnant women and poor sleep: medication is rarely the right solution

In the case of poor sleep during pregnancy, sedatives are rarely the right solution. Non-drug measures are preferable.
1 October 2018

Healthcare professionals are influenced by meals paid for by drug companies

Meals, even inexpensive ones, are very effective gifts because they exploit fundamental psychological reactions, promoting goodwill and making the beneficiary receptive to the sales message.
1 October 2018

"Top Texts of 2018", from the Editors of Prescrire International

 FREE SPECIAL EDITION  Check out this sampling of texts selected by our Editors to introduce you to Prescrire International, a wholly independent monthly journal, written by and for healthcare professionals.
1 October 2018

Smoking cessation: making repeated attempts with nicotine is safer than using varenicline (Champix° or Chantix°)

FEATURED REVIEW Varenicline, a partial agonist of nicotinic acetylcholine receptors, has been authorised since 2006 in the European Union for smoking cessation. In 2018, what is known about the harm-benefit balance of varenicline, and what role does it play in smoking cessation, compared to nicotine replacement therapy?
Full review (3 pages) available for download by subscribers.
1 September 2018

In the September issue of Prescrire International - Silver sulfadiazine cream: disproportionate adverse effects

FREE DOWNLOAD The antibacterial agent silver sulfadiazine has been marketed in France since the 1970s for use as an antiseptic. It has only a marginal place in treatment, as a last resort.
Full text available for free download.
1 September 2018

Telithromycin (Ketek°): a welcome market withdrawal

The company's decision to withdraw this antibiotic from the market is good news for patients, in view of the drug's negative harm-benefit balance. It is a pity that the European Medicines Agency did not muster the courage to order withdrawal of this drug long before.
1 September 2018

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