english.prescrire.org > Prescrire International > N°199 - December 2018

n°199

December 2018

Issue Contents
Editorial

Free  Exorbitant prices

p.283

New Products


Nasal naloxone (Nalscue°) in opioid overdose

p.285-287
Opioid antidote nasal spray, useful and convenient in an emergency

INN Common stem: -rolimus

p.287

Everolimus (Votubia°) for epilepsy associated with tuberous sclerosis complex

p.288-289
Primarily for patients with very troublesome partial seizures

Nusinersen (Spinraza°) in spinal muscular atrophy

p.290
Insufficient data

Levonorgestrel IUD 9 microg per day (Kyleena°)

p.291
No more effective, and no safer

Olmesartan and hypertension in children

p.292
Not acceptable

Inset. Advancing healthcare policy

p.292

Adverse Effects


Valproic acid and its derivatives: pregnancy prevention measures stepped up in the EU

p.293-294

Desloratadine: prolongation of QT interval added to the European Union SPC

p.294

Hormonal contraception: depression and suicide

p.295

Febuxostat: higher cardiovascular mortality than with allopurinol

p.295

Intravenous amoxicillin: crystalluria and acute renal failure

p.296

Fluoroquinolone + ACE inhibitor: acute kidney injury

p.296

Fluoroquinolones: aortic aneurysm and dissection

p.297

Hydrochlorothiazide: skin cancers

p.297

Reviews


Free  Stable angina and antithrombotic drugs

p.298
Addition of rivaroxaban to aspirin: uncertain benefits, proven harms

Queries and Comments. Omalizumab and severe persistent asthma

p.299-301
What is the harm-benefit balance as of 2018?

Outlook


Healthcare-related errors: describe them in detail to understand them better

p.302-306

Inset. Locating the error in the healthcare process

p.303

Inset. Improving the safety of transitions in care and before risky procedures

p.305

Free  Drugs for hepatitis C: it's time to slash prices!

p.307

Masthead


Free  Masthead

p.282

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