english.prescrire.org > Prescrire International > N°54 - August 2001

n°54

August 2001

Issue Contents
Editorial

Drugs agencies must be more open

p.98

New Products


Scopolamine: reference treatment for death rattle

p.99-101

Anticholinergic and atropinic effects

p.100

Trastuzumab: may help some patients with breast cancer, but too many unknowns

p.102-105

HER2 and breast cancer

p.104

Filgrastim: AIDS-associated neutropenia: another soft indication

p.106-107

Exemestane: no tangible advance in metastatic breast cancer after tamoxifen failure

p.108-109

Mitoxantrone: more risky than beneficial in advanced prostate cancer

p.110-112

Treatment of advanced prostate cancer

p.111

Disodium valproate: an alternative for acute mania after lithium failure or intolerance

p.113-115

Lithium to control acute mania

p.114

Quinupristin + dalfopristin: severe Gram-positive infections: a last resort for some patients

p.126

Desogestrel: the fifth oral progestogen-only contraceptive

p.127

Interferon alfa-2 and melanoma: only at low dose

p.127

Ethinylestradiol 15 µg + gestodene 60 µg: a lower strength combined contraceptive with no proven advantage

p.127

Adverse Effects


Nicotine substitutes and pregnancy

p.116-117

Ischaemic colitis on pseudoephedrine

p.117

Extrapyramidal effects of SSRI antidepressants

p.118-119

Stroke and phenylpropanolamine (continued)

p.120

Phenobarbital for mild sedation: market withdrawal

p.120

Reviews


Calcium channel blockers: third-line antihypertensives

p.121-123

Severe anaphylaxis outside the hospital setting

p.124-125

Diabetes: preventing severe foot lesions

p.126

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