english.prescrire.org > Prescrire International > N°108 - August 2010

n°108

August 2010

Issue Contents
Editorial

Free  Dispassionate assessment of the evidence

p.148
Emphasis on patients' best interests

Marketing Authorisations

Dronedarone (atrial fibrillation) (New drug)

p.149-152
Too many questions about long-term adverse effects

The dronedarone odyssey

p.150

Capsaicin (neuropathic pain) (New drug)

p.153-155
Not acceptable

Plerixafor (certain patients with lymphoma or myeloma) (New drug)

p.156-158
Only when G-CSF stem cell motilisation fails

Etoricoxib (osteoarthritis) (Now on sale)

p.158
Unacceptable

Golimumab (inflammatory rheumatism) (New drug)

p.159
Just another TNT alpha antagonist, no advantage

Losartan (hypertension in children) (New indication)

p.160
Third line option

Glatiramer (suspected multiple sclerosis) (New indication)

p.160
No proven advantage

INN common stems: -pristin

p.161

INN common stems: -tide

p.161

Adverse Effects

Cancer risk in diabetic patients treated with insulin glargine?

p.162-163
Dealing with uncertainties

Drug-induced restless legs syndrome

p.164-165
Mostly psychotropics

Secondary leukaemia: after umbilical cord blood stem cell transplantation too

p.166-167
A review of case reports

Risk of preterm delivery

p.168-169
A single course of antenatal corticosteroids is safer

Free  Lyell syndrome and epileptic seizures after confusion between Lamictal° and Lamisil°

p.169
Use the INN to avoid such errors

Propolis: hypersensitivity reactions

p.170
Natural but not harmless

Neuropathies due to denture adhesive overdose

p.171
Zinc is implicated

Negative-pressure wound therapy systems

p.171
Bleeding and infection

Becaplermin: infections

p.171
EMA data

Telbivudine: rhabdomyolysis and neuropathy

p.171
Lamivudine is safer

Reviews

Cervical cancer screening

p.172-179
Organised screening is best

Classification of cytological abnormalities of the cervix

p.174

Two techniques for cervical smear sampling

p.176

Screening based on papillomavirus detection: too many false alarms

p.178-179

Acute pyelonephritis in children

p.180
Antibiotic therapy depending on the clinical context

Arterial hypertension in children

p.181
Few clinical trials

Serenoa repens and benign prostatic hyperplasia

p.181-182
No more effective than placebo

Vitamins and minerals

p.182
Not for cancer or cardiovascular prevention

Outlook

ICH: an exclusive club of drug regulatory agencies and drug companies imposing its rules on the rest of the world

p.183-186

Conflicts of interest within the Afssaps French regulatory agency: more progress needed

p.186-188

Recognising expertise would help to attract independent experts

p.187

Measuring the quality of life of cancer patients: interpret the results with caution

p.188-190

Free  Pharmaceutical marketing: nurses are also targeted

p.190

Free  Prescrire's Solidarity Support Programme

p.192

Masthead

Free  Masthead

p.146

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