english.prescrire.org > Prescrire International > N°156 - January 2015

n°156

January 2015

Issue Contents
Editorial

Free  DSM-5: riddled with conflicts of interest

p.4
The American Psychiatric Association fails to ensure its independence

Marketing Authorisations

Sofosbuvir (Sovaldi°)

p.5-10
Active against hepatitis C virus, but evaluation is incomplete

No compelling reason to adopt new antivirals whenever it is reasonable to wait

p.8

INN common stem: -buvir

p.10

Vismodegib (Erivedge°)

p.11-14
In basal cell carcinoma: too many unknowns

Free  Strontium (Protelos°)

p.15
Still authorised despite an unfavourable opinion of the European pharmacovigilance committee

Adverse Effects

Semen abnormalities with SSRI antidepressants

p.16-17
Effects on fertility unclear

Ustekinumab: cutaneous disorders, malignancies,infections

p.17
Data from pharmacovigilance review

Drug-induced true vertigo and balance disorders

p.18
Sometimes accompanied by deafness

Miconazole and oral anticoagulants: bleeding

p.19
Oral gel and buccal tablets

NSAIDs and atrial fibrillation?

p.19
Consistent with other data

Cefepime: serious neurological adverse effects

p.20
Renal impairment is a risk factor

Pazopanib: retinal detachment

p.20
Patients should be informed

Lamotrigine: nightmares

p.20
Dose-dependent

Regorafenib: Dress

p.20-21
Yet another adverse effect

Electronic cigarettes: poisoning in children

p.21
Vomiting, eye irritation

Voriconazole: alopecia and nail changes

p.21
A productive survey

Ginkgo biloba: reduced efficacy of efavirenz

p.21
Two case reports

Reviews

Acute uncomplicated cystitis in women

p.22-24
The essentials of first-line management

Carpal tunnel syndrome and corticosteroid injections

p.24
Reduced symptoms, less need for surgery

Heart failure in sinus rhythm: no routine antithrombotic therapy

p.25
Harm-benefit balance appears unfavourable in this situation

Outlook

Ensuring the quality of articles published in Prescrire: the important role of reviewers

p.26-27
A diverse panel of reviewers

The high price of cancer drugs: enough is enough

p.27
A worldwide trend affecting even the wealthiest countries

Masthead

Free  Masthead

p.2

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