Editorial
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A drug company tried to exploit the conflicts of interest concept
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Marketing Authorisations
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Multiple sclerosis: just a metabolite of leflunomide
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With longer follow-up: even more toxic than suspected
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Biased evaluation, evidence of serious risks
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Adverse Effects
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Mostly in elderly men
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Beware of large cumulative doses
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Especially during long-term treatment
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Reviews
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Randomised trials: uncertain, at best modest, reduction in deaths from breast cancer
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71 drugs more harmful than beneficial
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Major implications for the efficient management of healthcare expenditure
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