english.prescrire.org > Prescrire International > N°191 - March 2018

n°191

March 2018

Issue Contents
Editorial

Free  EMA's opaque advice to drug companies

p.59

Marketing Authorisations

Methoxyflurane (Penthrox°) and emergency relief of acute pain in adults

p.61-63
Easier to use than nitrous oxide

Inset. Words and numbers to express pain

p.63

Nivolumab (Opdivo°) and Hodgkin lymphoma

p.63-65
Barely evaluated

Inset. What is graft-versus-host disease?

p.65

Brentuximab vedotin (Adcetris°) in Hodgkin lymphoma, immediately after autologous transplantation

p.65
Patients in remission are better spared the harms of this drug

Ceftazidime + avibactam (Zavicefta°)

p.66-67
An option in the case of cephalosporin resistance

INN Common stem: -retin-

p.68

Adverse Effects

Care of children in hospital: unnoticed errors are detected by the parents

p.69-70

Aripiprazole + another neuroleptic: pathological impulses and psychotic disorders

p.71

Rivaroxaban: musculoskeletal disorders

p.72

TNF-alpha inhibitors: neuropsychological effects

p.73

Reviews

Treatments for early syphilis

p.74-77
Benzathine benzylpenicillin is best; doxycycline and ceftriaxone as second choices

Gout attacks

p.77-78
A corticosteroid or an NSAID: similar efficacy

Prolonged seizures

p.78
A benzodiazepine first

Outlook

Free  2017 Prescrire Drug Awards

p.79-80

Free  The 2017 Prescrire's Awards

p.79-83

Free  2017 Prescrire Packaging Awards

p.81-82

Free  2017 Prescrire Information Awards

p.83

Masthead

Free  Masthead

p.58

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