english.prescrire.org > Prescrire International > N°220 - November 2020

n°220

November 2020

Issue Contents
Editorial

Free  Memory can save lives

p.255

Marketing Authorisations

Atezolizumab (Tecentriq°) in addition to cytotoxic drugs for some types of metastatic lung cancer

p.257-259
An increase in serious adverse effects, particularly when bevacizumab is also added

Lanadelumab (Takhzyro°) as long-term prophylaxis for hereditary angioedema attacks

p.259-261
An option when standard treatments fail or are poorly tolerated

Dapagliflozin (Forxiga°) and type 1 diabetes

p.262-263
Serious risks with no demonstrated clinical efficacy

Free  Dupilumab (Dupixent°) and nasal polyps

p.264

Editors' opinion. A common language

p.265

Drospirenone (Slinda°) and oral contraception

p.265-266

INN Common stem: -reno(ne)

p.266

Adverse Effects

Doxylamine during pregnancy: minimise dose and duration, due to possible link with malformations

p.267-269

Valproic acid during pregnancy: adverse effects on the third generation?

p.269-270

Inset. The Depakine° (valproic acid) scandal: Sanofi indicted for "aggravated deception" and "manslaughter"

p.270

Bupropion: spontaneous orgasms

p.271

Radioactive iodine for hyperthyroidism: more breast cancer deaths

p.271

Methylphenidate: performance-enhancing drug use by students

p.272

Intravenous iron: acute allergic coronary vasospasm

p.272

Reviews

Hypertension

p.273-274
Should blood pressure-lowering drugs be taken at bedtime?

Chronic hepatitis C

p.274
Glecaprevir + pibrentasvir: 8 weeks of treatment also for patients with compensated cirrhosis

Outlook

Placebo-controlled clinical trials: the use of "pure", "impure" and "false" placebos

p.275-278

Undemanding marketing authorisations in Europe and the USA, harmful consequences in Latin America too

p.278

Lorcaserin: withdrawal from the US market

p.279

What does conditional marketing authorisation mean?

p.279

Masthead

Free  Masthead

p.254

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