english.prescrire.org > Prescrire International > N°225 - April 2021

n°225

April 2021

Issue Contents
Editorial

Free  40 years

p.87

New Products


Larotrectinib (Vitrakvi°) and cancers with an NTRK gene fusion

p.89-91
Grossly inadequate evaluation as of early 2021

Editors' opinion. Dissuasion

p.90

INN Common stem: -taxel

p.91

Insulin lispro with treprostinil and sodium citrate as excipients (Lyumjev°)

p.92-93

Trastuzumab emtansine (Kadcyla°) for certain breast cancers, after surgery

p.93

Quadrivalent influenza vaccine containing 60 micro­grams per strain (Efluelda°) in the elderly

p.93

Atezolizumab (Tecentriq°) and certain small cell lung cancers

p.94

Atezolizumab (Tecentriq°) and inoperable or metastatic triple-negative breast cancer

p.95

Adverse Effects


Valproic acid: is it an endocrine disruptor?

p.96-100

Inset. Endocrine-disrupting drugs: their main effects on human hormone systems

p.98-99

Paclitaxel: peripheral neuropathy sometimes persisting more than 12 months

p.101

Lenograstim: venous and arterial thromboembolism

p.101

Ivermectin: coma in a child

p.102

Memantine: bradyarrhythmia

p.102

Vaginal progesterone: intrahepatic cholestasis of pregnancy

p.103

Queries and Comments. Food supplements: should consumers be reassured?

p.104

Reviews


Inset. Pomalidomide (Imnovid°) and multiple myeloma, after failure of lenalidomide

p.105

Relapsed or refractory multiple myeloma

p.105-106

Covid-19 and vitamin D: too uncertain

p.106

Free  Hydrochlorothiazide in hypertension

p.107
An accept­able first choice

Outlook


Free  Drugs in 2020: a brief review

p.108-109

Drug shortages: a (big) thorn in the side of pharma­cists

p.109

Free  Mediator°: norfenfluramine at the heart of the trial

p.110

Ulipristal (Esmya°): reintroduction to the market would be reckless

p.111

Sodium oxybate in alcohol dependence: marketing authorisation refused

p.111

Masthead


Free  Masthead

p.86

The complete contents of 
this issue of Prescrire International
are available for download by
Prescrire International subscribers.
Certain texts are also available to
non-subscribers for free download,
as indicated. 

 

Subscribe