Free  40 years

Marketing Authorisations

Larotrectinib (Vitrakvi°) and cancers with an NTRK gene fusion

Editors' opinion. Dissuasion

INN Common stem: -taxel

Insulin lispro with treprostinil and sodium citrate as excipients (Lyumjev°)

Trastuzumab emtansine (Kadcyla°) for certain breast cancers, after surgery

Quadrivalent influenza vaccine containing 60 micro­grams per strain (Efluelda°) in the elderly

Atezolizumab (Tecentriq°) and certain small cell lung cancers

Atezolizumab (Tecentriq°) and inoperable or metastatic triple-negative breast cancer

Adverse Effects

Valproic acid: is it an endocrine disruptor?

Inset. Endocrine-disrupting drugs: their main effects on human hormone systems

Paclitaxel: peripheral neuropathy sometimes persisting more than 12 months

Lenograstim: venous and arterial thromboembolism

Ivermectin: coma in a child

Memantine: bradyarrhythmia

Vaginal progesterone: intrahepatic cholestasis of pregnancy

Queries and Comments. Food supplements: should consumers be reassured?

Reviews

Inset. Pomalidomide (Imnovid°) and multiple myeloma, after failure of lenalidomide

Relapsed or refractory multiple myeloma

Covid-19 and vitamin D: too uncertain

Free  Hydrochlorothiazide in hypertension

Outlook

Free  Drugs in 2020: a brief review

Drug shortages: a (big) thorn in the side of pharma­cists

Free  Mediator°: norfenfluramine at the heart of the trial

Ulipristal (Esmya°): reintroduction to the market would be reckless

Sodium oxybate in alcohol dependence: marketing authorisation refused

Masthead

Free  Masthead