english.prescrire.org > Prescrire International > N°227 - June 2021

n°227

June 2021

Issue Contents
Editorial

Free  Covid-19 drugs and vaccines: big money and winning alliances

p.143

New Products


Tozinameran (Comirnaty°), covid-19 vaccine mRNA-1273 (Covid-19 vaccine Moderna°) and the covid-19 ­pandemic

p.145-147
Marked reduction in the risk of devel­oping covid-19, and no worrying safety signals

Inset. Messenger RNA covid-19 vaccines

p.146-147

Oral semaglutide (Rybelsus°)

p.148-150
More uncertainty than with subcutaneous liraglutide

Givosiran (Givlaari°) and acute hepatic porphy­ria

p.151
In the short term, a significant reduction in frequency of attacks

Trifarotene (Aklief°) and acne

p.152

Infliximab by subcutaneous injection (Remsima°)

p.153

Common stem: -glutide

p.153

Adverse Effects


Excessive iodine intake during pregnancy: hypothyroidism in the unborn child

p.154-156

Intravenous amoxicillin: crystal-induced acute kidney injury (continued)

p.157

Enzalutamide, apalutamide: interstitial lung disease

p.158

Testosterone: venous and arterial thrombosis

p.158

Memantine: dissociative disorders

p.159

Psychiatric adverse effects: also in children

p.159

Reviews


Pre-exposure prophylaxis for HIV (PrEP)

p.160-161
Useful for some high-risk patients

Free  Non-metastatic, castration-resistant prostate cancer

p.161
Survival extended with the addition of apalutamide or ­enzalutamide

Outlook


Oral cancer drugs: community pharmacists in France provide billable, structured care

p.162-164

Free  Waste in covid-19 clinical trials

p.164

Free  France's Mediator° trial: Servier and the French drug regulatory agency convicted and sentenced

p.165

Free  The finances of Association Mieux Prescrire: 2020 annual report

p.166-167

Masthead


Free  Masthead

p.142

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