english.prescrire.org > Prescrire International > N°239 - July 2022

n°239

July 2022

Issue Contents
Editorial

Free  Covid-19: delays in other types of health care

p.171

Marketing Authorisations

Rivaroxaban (Xarelto°) for venous thromboembolism in children and adolescents

p.173-175
An orally administered alternative

Anidulafungin (Ecalta°) in invasive candidiasis in children

p.175

Fostamatinib (Tavlesse°) in refractory chronic immune thrombocytopenia

p.176-177
Increases platelet count in some patients, but no demonstrated efficacy with respect to bleeding

Tucatinib (Tukysa°) in HER2-positive breast cancer, after failure of several HER2-directed drugs

p.178-179
Longer survival, but with a high incidence of serious adverse effects and drug interactions

Beclometasone + formoterol + glycopyrronium (Trimbow°) in asthma

p.180

Free  Indacaterol + glycopyrronium + mometasone (Enerzair Breezhaler°) in asthma

p.181

Free  Editors' opinion. Collected data

p.181

Pegvaliase (Palynziq°) in phenylketonuria

p.182
Reduction in blood phenylalanine levels, but no demonstrated clinical efficacy, plus anaphylactic reactions

Tralokinumab (Adtralza°) in atopic dermatitis in adults

p.183-184

A second covid-19 vaccine booster for some

p.184

Sotrovimab (Xevudy°) in covid-19

p.184

Dapagliflozin (Forxiga°) in chronic kidney disease

p.185

Lenalidomide (Revlimid°) in refractory or relapsed follicular lymphoma

p.185

Aducanumab and Alzheimer's disease: the EMA says no

p.186

Adverse Effects

Drug-induced abnormal body odour

p.187-189

Dinoprostone: fetal and neonatal death

p.189

Gabapentin and pregabalin result in the prescription of diuretics

p.190

Hydrochlorothiazide: acute respiratory distress

p.190

Intra-articular corticosteroids: rapid destruction of the hip joint

p.191

Aciclovir, valaciclovir: encephalopathy in the presence of renal failure (continued)

p.191

Neuroleptics: breast cancer

p.192

Common stem: -oxetine

p.192

Outlook

European legislation on orphan drugs and paediatric drugs

p.193

The European health-data space

p.193-194

Access to EMA documents

p.194

Commercial deals to delay introduction of generics: European companies fined

p.195

Corporate influence affects all types of medical publications

p.195

Masthead

Free  Masthead

p.170

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