Free  Flexibility

Marketing Authorisations

Tebentafusp (Kimmtrak°) in metastatic uveal melanoma

Ciltacabtagene autoleucel (Carvykti°) in multiple myeloma after failure of several treatments

Venetoclax (Venclyxto°) as first-line treatment for chronic lymphocytic leukaemia, in combination with obinutuzumab

Trastuzumab deruxtecan (Enhertu°) in relapsed metastatic breast cancer with low HER2 overexpression

Editors' opinion. Changing the rules

Teriflunomide (Aubagio°) in multiple sclerosis from 10 years of age

Remdesivir (Veklury°) in covid-19 at increased risk of progression to severe disease, or in children on oxygen

Pembrolizumab (Keytruda°) in non-metastatic triple-negative breast cancer before and after surgery

Nivolumab (Opdivo°) as adjuvant treatment for certain urothelial carcinomas at high risk of recurrence

Cabozantinib (Cabometyx°) in differentiated thyroid cancer following another VEGF inhibitor

Adding daratumumab (Darzalex°) in relapsed or refractory multiple myeloma

Vutrisiran (Amvuttra°) in polyneuropathy associated with transthyretin amyloidosis

Filgotinib (Jyseleca°) in men: reassuring data on testicular function, but still dangerous

Adverse Effects

Intravenous drug administration: frequent errors

Biotin: misleading thyroid function test results

Dupilumab, tralokinumab: corneal disorders

Ivermectin: toxic epidermal necrolysis and Stevens-Johnson syndrome

Hydroxychloroquine in the first trimester of pregnancy: an increase in malformations

Carbamazepine: diplopia

Erenumab and other CGRP inhibitors: alopecia

Common stem: -gepant

Outlook

Evaluation of new drugs and medical devices in Europe: a highly critical report from the KCE

Taking a blood pressure-lowering drug in the evening: major uncertainty regarding the benefit

Free  Diclofenac: also harmful for the environment

Queries and Comments. When should levodopa be taken: with meals or between meals?

Masthead

Free  Masthead