Regular post-marketing evaluation is needed

Marketing Authorisations

Ursodeoxycholic acid, primary biliary cirrhosis: dashed hopes

Sertraline: may help children with obsessive-compulsive disorder

Obsessive-compulsive disorder: behaviour therapy and drugs are only moderately effective

Combined acellular pertussis vaccines: no tangible benefit in primary vaccination

Pertussis vaccines: choice between efficacy and tolerability

Sublingual apomorphine in erectile disorders: a narrow therapeutic margin

Tibolone and menopausal symptoms: oestrogen-progestogen combinations are still the reference treatment

No androgen for sexual dysfunction after menopause

Tenecteplase, another thrombolytic agent for myocardial infarction: a slightly simpler treatment

Topical lidocaine + prilocaine: analgesia during mechanical debridement

Oral granisetron: avoids intravenous treatment durong highly emetic chemotherapy

Risedronic acid 5 mg

Lopinavir + ritonavir: still incomplete evaluation

Hepatitis A vaccine: batches with doubtful efficacy

Adverse Effects

Coxibs + oral anticoagulants: risk of interaction

Renal impairment due to topical NSAIDs

Heart failure on infliximab

Dr bupropion and Mr amfebutamone

Severe tuberculosis while on infliximab (cont'd)

Reviews

Creatine: little impact on athletic performance, but a risk of adverse effects

Ecstasy and pregnancy

Vasectomy

Outlook

Missing data

Very late withdrawal of fluorides

Tackling antibiotic waste: a public health priority