english.prescrire.org > Prescrire International > N°204 - May 2019

n°204

May 2019

Issue Contents
Editorial

Free  Antibiotics: no market, no interest

p.115

New Products


Lesinurad (Zurampic°) or lesinurad + allopurinol (Duzallo°) in gout

p.117-118
No therapeutic advance over probenecid

INN Common stem: -­profen, ­-­profen­-

p.118

Letermovir (Prevymis°) to prevent cytomegalovirus reactivation

p.119
Different adverse effect profile from that of other anti-CMV drugs

Cenegermin eye drops (Oxervate°) in neurotrophic keratitis

p.120
Efficacy in healing corneal lesions, but no improvement in vision

Free  Dupilumab (Dupixent°) in adults with atopic dermatitis

p.121
An option for very troublesome eczema after failure of ciclosporin

Pentosan polysulfate (Elmiron°) in bladder pain syndrome

p.122-123
A repurposed drug with no proven efficacy that can cause fatal thrombocytopenia

Adverse Effects


Drug-induced retinal disorders

p.124-127

Noscapine: acute abdominal pain

p.128

Angiotensin II receptor antagonists (ARBs): ­psoriasis

p.128

Reviews


Oral antihistamines and pruritus associated with skin disorders

p.129-131
Efficacy only demonstrated in chronic urticaria

Unconjugated pneumococcal vaccine and COPD

p.131-132
Less pneumonia, but no proven effect on risk of hospital admission

Outlook


Vaccine hesitancy: understanding it better, to provide better support

p.133-137

Drugs for Alzheimer's disease: reduction in the number of prescriptions too slow

p.138

Free  Normalisation of school behaviour with methylphenidate

p.139

Masthead


Free  Masthead

p.114

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