english.prescrire.org > Prescrire International > N°213 - March 2020

n°213

March 2020

Issue Contents
Editorial

Free  Protecting patients

p.59

Marketing Authorisations

Darvadstrocel (Alofisel°) for complex perianal fistulae in Crohn's disease

p.61-64
A rash marketing authorisation decision

Ertugliflozin (Steglatro° and combination products) in type 2 diabetes

p.65

Free  Dengue vaccine (Dengvaxia°)

p.66
Not for large-scale use

Ataluren (Translarna°) and Duchenne muscular dystrophy in children aged 2 to 4 years

p.67

Cerliponase alfa (Brineura°) and neuronal ceroid lipofuscinosis type 2

p.67

Dimethyl fumarate and psoriasis: Transparency Committee of the French National Authority for Health opposed to its reimbursement

p.68

Adverse Effects

Rotarix° oral vaccine: still being mistakenly administered by intramuscular injection

p.69-70

Paracetamol in late pregnancy: a risk factor for premature closure of the ductus arteriosus

p.71-72

Empagliflozin (Jardiance°): unlikely to be marketed in France

p.72

Metamizole (dipyrone): agranulocytosis and fetotoxicity

p.73-74

Padeliporfin: two committees of the French National Authority for Health opposed to its reimbursement

p.74

Reviews

Painful endometriosis

p.75
If not planning a pregnancy: paracetamol and NSAID, or a combined oral contraceptive, or a levonorgestrel IUD

Blood pressure below 160/100 mm Hg

p.76
In the absence of other risk factors, antihypertensive drugs are not justified

Outlook

Free  2019 Prescrire Drug Awards

p.77-78

Free  The Prescrire Awards for 2019

p.77-81

Free  2019 Prescrire Packaging Awards

p.79-80

Free  2019 Information Awards

p.81

Olaratumab: withdrawal of a mistakenly-granted marketing authorisation

p.82

Free  Meta-analyses: learn to question their reliability

p.83

Masthead

Free  Masthead

p.58

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