english.prescrire.org > Prescrire International > N°216 - June 2020

n°216

June 2020

Issue Contents
Editorial

Free  Curiosity

p.143

New Products


Subcutaneous prolonged-release buprenorphine (Buvidal°) and opioid dependence

p.145-146
Another option, with different routes of administration

Dabrafenib (Tafinlar°) and trametinib (Mekinist°) combined, as adjuvant therapy for stage III melanoma with a BRAF V600 mutation

p.147-149
Lower risk of recurrence, but more adverse effects and no comparison with other antineoplastics

Pembrolizumab (Keytruda°) as adjuvant therapy for stage III melanoma

p.149

Nivolumab (Opdivo°) as adjuvant therapy for stage III and stage IV of melanoma

p.150-151

INN Common stem: -parin(ux)

p.151

Adverse Effects


Tramadol: increased mortality?

p.152-153

Inset. Millions of patients exposed to tramadol in France every year

p.153

Weekly methotrexate: welcome measures to ­prevent fatal errors

p.154-155

Incretin-based hypoglycaemics (gliptins and GLP-1 agonists): intestinal obstruction

p.155

Carbamazepine: loss of so-called absolute pitch

p.156

Aloe vera: hepatitis

p.156

Fraudulent food supplement: stroke

p.157

Vinpocetine: teratogenic

p.157

Reviews


Inset. Peppermint essential oil (Colpermin°) and non-serious intestinal disorders

p.158

"Antispasmodics" for abdominal pain

p.158-159

Free  Inset. Antispasmodics during pregnancy, in brief

p.159

Subclinical hypothyroidism

p.160
No proof of benefit from treatment with thyroid hormone

Fosfomycin trometamol during the first trimester of pregnancy: new data

p.160

Outlook


Free  Drug-induced heart valve disease: a blind spot for cardiologists

p.161-164

France's supreme administrative jurisdiction confirms the importance of abolishing umbrella brands

p.165

Drug prices: European countries join forces

p.165

Free  The finances of Association Mieux Prescrire: 2019 annual report

p.166-167

Masthead


Free  Masthead

p.142

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