english.prescrire.org > Prescrire International > N°221 - December 2020

n°221

December 2020

Issue Contents
Editorial

Free  An exemplary initiative

p.283

Marketing Authorisations


Fexinidazole (Fexinidazole Winthrop°) and sleeping sickness caused by Trypanosoma brucei gambiense

p.285-289
Effective and more convenient than injectable treatments

Editors' opinion. Development of fexinidazole: a product of exemplary collaboration

p.289

Free  Betibeglogene autotemcel (Zynteglo°) in certain forms of severe beta thalassaemia

p.290-291
An option for achieving transfusion independence in the absence of a compatible donor

Free  Editors' opinion. The European Priority Medicines ("Prime") scheme cements industry influence over early marketing authorisation

p.291

Meropenem + vaborbactam (Vaborem°) and serious infections

p.292-293
A backup option in cases of carbapenem resistance

Volanesorsen (Waylivra°) and familial chylo­micronemia syndrome

p.294

INN Common stem: -penem

p.294

Adverse Effects


Drug-induced pericarditis

p.295-298

Citalopram + omeprazole: sudden cardiac death

p.298

Bimatoprost and similar eye drops: enophthalmos

p.299-300

Mecasermin: benign and malignant tumours

p.300

Degarelix: rhabdomyolysis

p.300

Reviews


Relief of moderate nociceptive pain in breastfeeding women

p.301-302
Non-pharmacological measures first, then paracetamol or ibuprofen

Lung cancer with a del19 EGFR mutation

p.302
Survival extended with osimertinib as first-line therapy

Outlook


Free  Drug research: public funding, private profits

p.303-306

Oxycontin°: regulation conferred protection in some states in the US

p.306

Free  Mediator°: all wrong from the very start

p.307

Masthead


Free  Masthead

p.282

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