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Marketing Authorisations

Solriamfetol (Sunosi°) and sleepiness due to narcolepsy or sleep apnoea

Inset. Solriamfetol: similar chemical structure and pharmacological effects to other amphetamines

Tezacaftor + ivacaftor (Symkevi°) and cystic fibrosis with the F508del mutation from 12 years of age

Pembrolizumab (Keytruda°) as first-line treatment for certain metastatic or recurrent head and neck cancers

Ramucirumab (Cyramza°) as first-line treatment for certain lung cancers

Isatuximab (Sarclisa°) as third-line or subsequent treatment for multiple myeloma

Free  Fusidic acid + betamethasone valerate cream (Dermafusone°) and infected atopic eczema

INN Common stem: -meran, -siran

Adverse Effects

Drug-induced arterial aneurysm and dissection

Perampanel: Stevens-Johnson syndrome and serious liver disorders

Editors' opinion. Sounding the alarm

Proton pump inhibitors: know how to avoid unjustified risks and how to "deprescribe"

Low-dose methotrexate: 2-year follow-up of adverse events

Fingolimod: serious liver injury, sometimes ­requiring transplantation

Neuroleptics: acute respiratory failure

Reviews

Human papillomavirus vaccine in men

Editors' opinion. HPV vaccination: useful for some, possibly for all

Prescrire's proposals. HPV vaccination in men: talk about it

Outlook

Food supplements: poorly evaluated and moni­tored, too readily authorised, and sometimes dangerous

Editors' opinion. Food supplements: what part can healthcare professionals play?

Jordi Llinares: Sometimes the unknowns are even more important than what is known

Withdrawal of reimbursement for Alzheimer's drugs and exposure to psychotropics

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