english.prescrire.org > Prescrire International > N°270 - May 2025

n°270

May 2025

Issue Contents
Editorial

Free  Why drugs should be evaluated in several randomised comparative trials

p.115

Marketing Authorisations


Apomorphine sublingual film (Kynmobi°) in "off" episodes in Parkinson's disease

p.117-118

Linzagolix (Yselty°) in uterine fibroids

p.118-119

Editors' opinion. Another cascade

p.119

Cabotegravir (Apretude°) in HIV pre-exposure prophylaxis (PrEP)

p.120-121

Selpercatinib (Retsevmo°) as first-line treatment in metastatic RET fusion-positive lung cancer

p.121-122

Selpercatinib (Retsevmo°) as first-line treatment in certain thyroid cancers

p.122

Elranatamab (Elrexfio°) in multiple myeloma after at least 3 lines of treatment

p.123

Lanadelumab (Takhzyro°) in the long-term prevention of hereditary angioedema attacks in children

p.124-125

Talazoparib (Talzenna°) + enzalutamide in metastatic prostate cancer resistant to androgen deprivation therapy

p.125-126

Glofitamab (Columvi°) as third- or subsequent-line treatment in diffuse large B-cell lymphoma

p.126

Phloroglucinol: meagre evaluation and notable risks, especially when taken by young women

p.127-129

Agomelatine in depression: no marketing authorisation in adolescents

p.129-130

Insulin lispro with treprostinil and sodium citrate as excipients (Lyumjev°) from 1 year of age

p.130

Adverse Effects


Myocarditis linked to messenger RNA covid-19 vaccines (continued)

p.131-133

Pralsetinib: severe infections, even without neutropenia

p.133

Nalmefene + opioids: serious withdrawal symptoms

p.134

Acetazolamide: acute pulmonary oedema

p.134

Antidepressants: higher incidence of withdrawal symptoms with venlafaxine

p.135

Common stem : -parib

p.135

Outlook


Free  2024 Prescrire Drug Awards

p.136-137

Free  The Prescrire Awards for 2024

p.136-139

Free  2024 Prescrire Packaging Awards

p.137-138

Free  2024 Prescrire Information Awards

p.139

Masthead


Free  Masthead

p.114

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