english.prescrire.org > Prescrire International > N°272 - July 2025

n°272

July 2025

Issue Contents
Editorial

Free  New drugs: improve information about uncertainties

p.171

Marketing Authorisations


Inclisiran (Leqvio°) in certain types of hypercholesterolaemia

p.173-175

Editors' opinion. Narrow view

p.174

Alirocumab (Praluent°) in heterozygous familial hypercholesterolaemia from 8 years of age

p.175

Somapacitan (Sogroya°) in growth hormone deficiency in adults

p.176-177

Somapacitan (Sogroya°) in growth failure

p.177

Abaloparatide (Eladynos°) in postmenopausal osteoporosis

p.178-179

Zilucoplan (Zilbrysq°) in generalised myasthenia gravis

p.179-180

Ribociclib (Kisqali°) tablets: shelf life and storage conditions modified because of an impurity

p.180

Rezafungin (Rezzayo°) in invasive candidiasis

p.181

Pegylated epoetin beta (Mircera°) in anaemia associated with chronic kidney disease from 3 months of age

p.182

Eculizumab (Soliris°) in myasthenia gravis from 6 years of age

p.182

Pembrolizumab (Keytruda°) in the first-line treatment of certain biliary tract cancers

p.183

Omalizumab (Xolair°) 300-mg dose strength and pre-filled pens

p.183

Ipilimumab + nivolumab as first-line therapy for inoperable or metastatic melanoma: not shown to extend survival

p.184

Hypertension: follow-up of Allhat participants

p.185

Adverse Effects


Antineoplastic drugs + PPIs: shorter survival

p.186-187

High cumulative doses of opioids during pregnancy: long-term neuropsychiatric harms in exposed children

p.188-189

Gabapentin or pregabalin in neuro­pathic pain in children: a review of adverse effects

p.190

Pregabalin, gabapentin: hip fractures

p.191

GLP-1 agonist or tirzepatide + levothyroxine: adjust the dose of levothyroxine according to body weight

p.191

Sulfonamides, cephalosporins, nitrofurantoin: severe cutaneous adverse reactions

p.192

Denosumab for bone metastases: frequent osteonecrosis of the jaw

p.192

Common stem: ­-poetin

p.193

Common stem: -mycin

p.193

Outlook


Free  Conflicts of interest in European health technology assessments

p.194

Free  EMA: protecting personal data and commercially confidential information

p.194

Free  EMA: assessing the risks of drugs for human reproduction and lactation

p.194

Androcur° (cyproterone): multiple lawsuits in progress or in preparation in France

p.195

Masthead


Free  Masthead

p.170

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