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Marketing Authorisations

Bempedoic acid (Nilemdo°) or bempedoic acid + ezetimibe (Nustendi°) in cardiovascular prevention

RAdamts13 (Adzynma°) in congenital thrombotic thrombocytopenic purpura

Trastuzumab emtansine (Kadcyla°) in certain breast cancers, after neoadjuvant treatment with trastuzumab + chemotherapy and surgery

Editors' opinion. New data

Ranibizumab for intravitreal administration : prefer pre-filled syringes

Tirzepatide (Mounjaro°) in excess body weight

Fruquintinib (Fruzaqla°) in metastatic colorectal cancer

Recombinant crisantaspase (Enrylaze°) as an alternative to E. coli-derived asparaginase in certain haematological malignancies

Azithromycin: some indications refined and others removed due to increased bacterial resistance

Lenalidomide: defective capsules, but no batch recall

Adverse Effects

GLP-1 agonists in pregnancy: poorly elucidated risks that warrant a highly cautious approach

Inset. GLP-1 agonists: caution with concomitant use of oral hormonal contraceptives or drugs with a narrow therapeutic index

GLP-1 agonists: colonoscopy failure

Queries and comments. Cardiovascular effects of metopimazine: myth or reality?

Antiepileptics: osteoporosis and fractures

Etonogestrel contraceptive implants and obesity: efficacy uncertain in the third year

Gliflozins: phimosis and paraphimosis

Common stem: ­-quine

Outlook

Drug shortages: tougher financial penalties in France

Countering the influence of the pharmaceutical and medical devices industry in Europe

Drug shortages: proposed European legislation

EMA: electronic product information

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