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In the July-August issue of Prescrire International: aflibercept (Eylea°) in diabetic macular oedema without visual impairment

FREE DOWNLOAD What is the efficacy of aflibercept in patients with diabetic macular oedema without visual impairment at the time of diagnosis?
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In practice

  • For diabetic patients who have macular oedema with no loss of visual acuity, treatment from the outset with intravitreal injections of a aflibercept does not seem to offer any tangible advantage compared to observation in preventing deterioration of visual acuity.
     
  • There is no justification for early exposure of patients to the sometimes serious adverse effects of this anti‐VEGF.
     
  • It is better to reserve its use for patients with marked or worsening visual impairment.

©Prescrire 1 July 2020

Source: "Diabetic macular oedema without visual impairment. No benefit from immediate treatment with aflibercept" Prescrire International 2020; 29 (217): 190. Free.

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