Each month the editorial staff presents
systematic and comparative
analyses of available data on
all newly approved drugs in France,
and on new therapeutic indications
granted for existing drugs. The aim is to
help the reader to distinguish, among
the plethora of lavishly promoted new
commercial products (despite the failings
of the licensing authorities), those
medications worth adding to their drug
list or using instead of existing drugs.
This evaluation follows rigorous procedures
(details on www.prescrire.org)
that include a thorough literature
search, a large panel of reviewers (specific
to each drug), and a quality control
system to check, among other
things, that the text is consistent with
the references.
Independence
This work is carried
out in total independence: our activities
are financed exclusively by individual
readers’ subscriptions: neither
the French nor the English edition carries
any paid advertising, nor do we
receive grants or subsidies of any kind
(see our annual financial report).
At the end of each year, the Prescrire
Drug Awards are based on review articles
published that year. Note that the
selection process takes into account
any new data available since the initial
article was published.
The rules governing the Drug Awards
are also available on the Prescrire website
at www.prescrire.org.
Therapeutic advance is defined as
better efficacy, fewer or less severe
adverse effects (for the same efficacy),
or safer or more convenient administration.
2007: therapeutic progress for
some patients
As in 2006, we considered
that a drug introduced to the
French market during the previous
year deserved the Golden Pill award . However, very few
patients will benefit from this therapeutic
advance. In the vast majority of
clinical situations the lack of real innovation
continues. And, unable to introduce
enough new drugs to the market that
represent a tangible therapeutic
advance, most drug companies are simply
marking time, cutting up the indications
for their existing products into thinner and thinner slices, using
numerous strategies to exploit their
remaining patents to the fullest, and
are using and abusing advertising in
all its different forms to boost sales.
In this stagnant situation, what
patients need most are more dynamic
and demanding regulatory authorities.
©Prescrire April 2008
Source: Prescrire Int 2008; 17 (94): 75.