english.prescrire.org > Spotlight > Archives : 2009 > In the April issue of Prescrire International:duloxetine in generalised anxiety too?

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In the April issue of Prescrire International:
duloxetine in generalised anxiety too?

FREE DOWNLOADDuloxetine (Cymbalta°) in generalised anxiety? No thanks! There is no tangible efficacy but numerous and sometimes severe adverse effects.
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  • Duloxetine has now been approved in the EU for the treatment of generalised anxiety, even though it has not been compared with a short course of benzodiazepine treatment.
  • Duloxetine carries an even higher risk of adverse effects and interactions than "selective" serotonin reuptake antidepressants.

    Editors' Opinion
  • Lilly is doing everything possible to make duloxetine profitable, in indications as varied as stress urinary incontinence, depression, neuropathic pain, and now generalised anxiety. But does this psychotropic drug really represent a panacea?
  • A closer look at the evidence shows that the opposite is true: efficacy is uncertain, while adverse effects are numerous and sometimes serious.