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2020

Antiepileptics and pregnancy: potential long-term effects in children

FEATURED REVIEW Many women who could become pregnant are exposed to antiepileptic drugs. Yet most of the antiepileptic drugs taken by pregnant women expose the unborn child to the risk of malformations, fetotoxic effects and neonatal disorders. What are the long-term effects of the most widely used antieleptics on children exposed in utero, and how do they compare?
Full review (8 pages) available for download by subscribers.

1 January 2020

In the January issue of Prescrire International - Dapagliflozin in type 2 diabetes: no advance in terms of cardiovascular complications

FREE DOWNLOAD In the "Reviews" section this month: what is dapagliflozin's harm-benefit balance in type 2 diabetes, in light of the results of a recent randomised, double-blind trial studying the drug's effect on cardiovascular outcomes?

Full text available for free download.

1 January 2020

Persistent psychotic disorders: avoid combining neuroleptics

Combining oral neuroleptics cumulates adverse effects but offers no proven benefits.

1 January 2020

The common cold: echinacea purpurea is no better than placebo

There is no known drug, herbal medicine or other remedy that reduces the intensity or duration of cold symptoms and has a favourable harm-benefit balance.

1 January 2020

Vitamin B6: overdoses leading to neuropathies

With few exceptions, consuming vitamin B6 in addition to food has no medical justification and can lead to overdoses with peripheral neuropathies.

1 January 2020