In 2008 the prices of new drugs continued
to bear little relation to the therapeutic
advantage provided to patients.
Ever higher prices
Examples include
the €2000 price granted for dexrazoxane
treatment of anthracycline extravasation in
France, even though this drug had no
proven advantages over existing options
(Prescrire International 97); and the €35 000
per month for idursulfase therapy for a
child with mucopolysaccharidosis type II
who weighs 30 kg, even though the benefits
of this recombinant enzyme had not been demonstrated (Prescrire
International 95).
The price of glitazones, recent antidiabetic
drugs with unfavourable risk-benefit
balances, is still far higher than that
of metformin (an older standard antidiabetic
drug), despite the fact that the
French Transparency Committee that
assesses the medical benefits of new
drugs and provides recommendations
concerning drug reimbursement] lowered
their rating for these drugs (la revue Prescrire 301 p. 818).
©Prescrire April 2009
Source: Prescrire Int 2009; 18 (100): 84-88.