english.prescrire.org > Spotlight > Archives : 2010 > In the October issue of Prescrire International: ketoprofen gels, unfortunately back on the French market

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In the October issue of Prescrire International:
ketoprofen gels, unfortunately back on the French market

FREE DOWNLOAD Ketoprofen gels are more harmful than beneficial, and their withdrawal from the French market in late 2009 was a welcome measure. Unfortunately, they were back on the market in early 2010 following legal action. Healthcare professionals and patients should rely on solid evidence rather than decisions made by regulatory agencies or the judiciary.
Full text available for free download.

Summary

  • There has long been evidence that ketoprofen gels are more harmful than beneficial in patients with mild disorders.
     
  • These products carry a risk of frequent and potentially severe cutaneous disorders but have only modest efficacy, at best.
     
  • When a topical NSAID is indicated, it is better to choose ibuprofen or diclofenac which cause fewer cutaneous disorders than ketoprofen.
     
  • One lesson to be learned from this case is that patients and healthcare professionals should base their decisions on solid, relevant and independent data rather than relying on decisions made by regulatory agencies or the judiciary. 

 ©Prescrire 1 October 2010

"Ketoprofen gels" Prescrire Int 2010 ; 19 (109) : 204-205. (Pdf, free)
Download the full review