english.prescrire.org > Spotlight > Archives : 2022 > In the May issue of Prescrire International: Pertuzumab + trastuzumab (Phesgo°) by subcutaneous injection, in certain types of breast cancer

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In the May issue of Prescrire International: Pertuzumab + trastuzumab (Phesgo°) by subcutaneous injection, in certain types of breast cancer

FREE DOWNLOAD A solution for subcutaneous injection containing a fixed-dose combination of these two anti-HER2 monoclonal antibodies has been authorised in the EU. How do Prescrire's editors rate this combination in its new form?
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Prescrire's rating

  OFFERS AN ADVANTAGE  Subcutaneous injection is quicker than intravenous administration. In Europe, this drug is restricted to hospital use. The harm-benefit balance of pertuzumab + trastuzumab is only favourable in women with inoperable breast cancer. 


©Prescrire 1 May 2022

Source: "Pertuzumab + trastuzumab (Phesgo°) by subcutaneous injection, in certain types of breast cancer" Prescrire International 2022; 31 (237): 123. Free.

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See also:

"Prescrire's ratings for new
drugs and new indications"
(February 2022)
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"Pertuzumab and metastatic
breast cancer. Longer
survival confirmed, but
cardiac risks to be monitored"
Prescrire Int 2017;
26 (184): 178-179.
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