english.prescrire.org > Spotlight > Archives : 2026 > Cerliponase alfa (Brineura°) in neuronal ceroid lipofuscinosis type 2 disease: new data

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Cerliponase alfa (Brineura°) in neuronal ceroid lipofuscinosis type 2 disease: new data

 Marketing Authorisations  In the light of current data, does enzyme replacement therapy with cerliponase alfa enable children with neuronal ceroid lipofuscinosis type 2 (CLN2) disease to lead a life without disabilities? Does it extend survival? And what are its adverse effects?
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 ©Prescrire 1 May 2026

Source: "Cerliponase alfa (Brineura°) in neuronal ceroid lipofuscinosis type 2 disease" Prescrire Int 2026; 35 (281): 126-127. Subscribers only.

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See also:
 
"Cerliponase
alfa - Brineura°
and neuronal ceroid
lipofuscinosis type 2"
Prescrire Int 2020;
29 (213): 67.
Subscribers only