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Antineoplastic drugs + PPIs: shorter survival

 Adverse Effects  What are the main evaluation data on the risk of excess mortality with concomitant exposure to an antineoplastic drug and a proton pump inhibitor? To what extent do these data help in making healthcare decisions?
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 ©Prescrire 1 July 2025

Source: "Antineoplastic drugs + PPIs: shorter survival" Prescrire Int 2025; 34 (272): 186-187. Subscribers only.

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See also:

"Proton pump inhibitors:
increased mortality"
Prescrire Int 2019;
28 (200): 13-15.
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"Overprescription of PPIs:
increased mortality
and morbidity"
Prescrire Int 2025;
34 (271): 164.
Subscribers only

"Proton pump inhibitors:
how to avoid unjustified risks
and how to 'deprescribe'"
Prescrire Int 2021;
30 (228): 186-187.
Subscribers only