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In-utero exposure to mesalazine: renal disorders, haematological disorders and possibly malformations

 Adverse Effects  A group of French regional pharmacovigilance centres analysed several reports of renal disorders in children who had been exposed in utero to mesalazine. Other data on first-trimester exposure suggest a higher risk of major malformations in exposed children than in unexposed children, mainly cardiovascular defects.
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 ©Prescrire 1 July 2026

Source: "In-utero exposure to mesalazine: renal disorders, haematological disorders and possibly malformations" Prescrire Int 2026; 35 (283): 184-185. Subscribers only.

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