english.prescrire.org > Spotlight > 100 most recent > In the June issue of Prescrire International: Dabigatran (Pradaxa°) in deep vein thrombosis and pulmonary embolism

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In the June issue of Prescrire International: Dabigatran (Pradaxa°) in deep vein thrombosis and pulmonary embolism

FREE DOWNLOAD In the New Products section of the June issue: compared with adjusted-dose warfarin, dabigatran provides no tangible advantages for patients with pulmonary embolism or deep vein thrombosis. Warfarin remains the standard drug.
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Summary

  • The anticoagulant dabigatran was not more effective than warfarin in three "non-inferiority" trials.
     
  • Less bleeding but more acute coronary events with dabigatran, and still no antidote.
     

Full text available for free download.

 ©Prescrire 1 June 2015

"Dabigatran (Pradaxa°): deep vein thrombosis and pulmonary embolism" Prescrire Int 2015; 24 (161): 150. (Pdf, free)
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