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Nasal naloxone (Nyxoid°): effective in opioid overdoses

A new naloxone-containing nasal spray (Nyxoid°) has been authorised in the European Union for emergency use in medical and non-medical settings in adults and adolescents aged 14 years and over. How do Prescrire's editors rate this product in its new form?

Prescrire's rating

  OFFERS AN ADVANTAGE  Nasal naloxone is effective at preventing death in the event of an opioid overdose resulting from medical or illicit opioid use. It has a favourable harm-benefit balance in both medical and non-medical settings.

©Prescrire 1 February 2022

Source: "Nasal naloxone 1.8 mg (Nyxoid°) in opioid overdose" Prescrire International 2022; 31 (234): 42. Subscribers only.

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See also:
"Opioid overdose:
an antidote to be
administered promptly"
(December 2018)
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