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High cumulative doses of opioids during pregnancy: long-term neuropsychiatric harms in exposed children

 Adverse Effects  When a pregnant woman experiences pain that is severe or not relieved by paracetamol, an opioid is sometimes justified. In 2024, new data were published on the long-term neurodevelopmental and neuropsychiatric harms of in-utero exposure to opioids.
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 ©Prescrire 1 July 2025

Source: "High cumulative doses of opioids during pregnancy: long-term neuropsychiatric harms in exposed children" Prescrire Int 2025; 34 (272): 188-189. Subscribers only.

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See also:
 
"Opioid replacement therapy
during pregnancy: buprenorphine
appears less dangerous than
methadone for the unborn child"
Prescrire Int 2024;
33 (262): 216.
Subscribers only